Action Bimectin Plus combines two active ingredients—ivermectin and clorsulon—providing a broad spectrum of activity against gastrointestinal and pulmonary nematodes (adults, larvae 3 and 4, and inhibited stages), trematodes (adults and immature), mites, and insects.
Ivermectin works by increasing the permeability of the cell membrane to chloride ions, causing hyperpolarization of the nerve or muscle cells, leading to paralysis and death of the parasite. It also promotes the secretion of gamma-aminobutyric acid at the synapses of the parasites, interrupting nerve impulses.
Clorsulon acts on trematodes, both immature and mature, by inhibiting enzymes in the glycolytic cycle.
Indications For cattle in the treatment of infestations caused by:
Trematodes (adults and immature): Fasciola hepatica and Fasciola gigantica.
Scabies: Sarcoptes scabiei var bovis, Choroptes bovis, and Psoroptes bovis.
Ectoparasites: Linognathus vituli, Haematopinus eurysternus, Damalinia bovis, and ticks.
Method of Administration Bimectin Plus is administered strictly subcutaneously in cattle at a dosage of 1 ml per 50 kg of body weight, providing 0.2 mg of ivermectin and 2 mg of clorsulon per kg of body weight.
Contraindications and Precautions Avoid administering more than 10 ml of Bimectin Plus at a single site.
Withdrawal Period For meat and organs: 66 days.
Storage Conditions Store at temperatures between 15 - 25°C, protected from direct sunlight.
Presentation Bottle containing 250 ml of solution.
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